High-Grade Serous Carcinoma

Overview

High-grade serous carcinoma is the most aggressive and common subtype of epithelial ovarian cancer.

Symptoms

• •Ascites
• •Abdominal distension
• •Weight loss
• •Fatigue

Stages

Diagnosis

• ✓CA-125 elevation
• ✓CT/PET-CT
• ✓Biopsy
• ✓p53 mutation

Treatments

• →Debulking surgery
• →Carboplatin + Paclitaxel
• →Bevacizumab
• →Olaparib

Risk Factors