Lynch Syndrome

Overview

Lynch syndrome is hereditary nonpolyposis colorectal cancer (HNPCC).

Symptoms

• •Early-onset colorectal cancer
• •Family history of cancer

Stages

Diagnosis

• ✓IHC for MMR proteins
• ✓Genetic testing (MLH1, MSH2, etc.)

Treatments

• →Annual colonoscopy
• →Aspirin prophylaxis
• →Risk-reducing surgery

Risk Factors