Stomach Cancer
Gastrointestinal Stromal Tumor (GIST)
GIST is a sarcoma of the GI tract, driven by KIT or PDGFRA mutations.
Prevalence:nadir
Overview
GIST is a sarcoma of the GI tract, driven by KIT or PDGFRA mutations.
Signs & Symptoms
- •Abdominal pain
- •GI bleeding
- •Early satiety
- •Mass
Causes & Risk Factors
Neurofibromatosis type 1, Familial GIST
Diagnosis
CT abdomen, Endoscopy, Biopsy, KIT/PDGFRA testing
Treatment Options
Surgical resection, Imatinib (Gleevec), Sunitinib, Regorafenib